Synergistic Utilization of Necrostatin-1 and Z-VAD-FMK Efficiently Promotes the Survival of Compression-Induced Nucleus Pulposus Cells via Alleviating Mitochondrial Dysfunction

We recently reported that necroptosis contributed to compression-induced nucleus pulposus (NP) cells death. In the current study, we investigated the regulative effect of necroptosis inhibitor Necrostatin-1 on NP cells apoptosis and autophagy. Necrostatin-1, autophagy inhibitor 3-Methyladenine and a...

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Detalles Bibliográficos
Autores principales: Chen, Songfeng, Tian, Qing, Shang, Chunfeng, Yang, Lin, Wei, Na, Shang, Guowei, Ji, Yanhui, Kou, Hongwei, Lu, Shitao, Liu, Hongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738793/
https://www.ncbi.nlm.nih.gov/pubmed/33376733
http://dx.doi.org/10.1155/2020/6976317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738793/
https://www.ncbi.nlm.nih.gov/pubmed/33376733
http://dx.doi.org/10.1155/2020/6976317

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