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Brain-derived neurotrophic factor precursor in the immune system is a novel target for treating multiple sclerosis

Rationale: Brain-derived neurotrophic factor precursor (proBDNF) is expressed in the central nervous system (CNS) and the immune system. However, the role of proBDNF in the pathogenesis of multiple sclerosis (MS) is unknown. Methods: Peripheral blood and post-mortem brain and spinal cord specimens w...

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Detalles Bibliográficos
Autores principales: Hu, Zhao-Lan, Luo, Cong, Hurtado, Plinio Reinaldo, Li, Hui, Wang, Shuang, Hu, Bo, Xu, Jun-Mei, Liu, Yang, Feng, Shi-Qing, Hurtado-Perez, Ernesto, Chen, Kang, Zhou, Xin-Fu, Li, Chang-Qi, Dai, Ru-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738849/
https://www.ncbi.nlm.nih.gov/pubmed/33391501
http://dx.doi.org/10.7150/thno.51390