Cargando…
Brain-derived neurotrophic factor precursor in the immune system is a novel target for treating multiple sclerosis
Rationale: Brain-derived neurotrophic factor precursor (proBDNF) is expressed in the central nervous system (CNS) and the immune system. However, the role of proBDNF in the pathogenesis of multiple sclerosis (MS) is unknown. Methods: Peripheral blood and post-mortem brain and spinal cord specimens w...
Autores principales: | Hu, Zhao-Lan, Luo, Cong, Hurtado, Plinio Reinaldo, Li, Hui, Wang, Shuang, Hu, Bo, Xu, Jun-Mei, Liu, Yang, Feng, Shi-Qing, Hurtado-Perez, Ernesto, Chen, Kang, Zhou, Xin-Fu, Li, Chang-Qi, Dai, Ru-Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738849/ https://www.ncbi.nlm.nih.gov/pubmed/33391501 http://dx.doi.org/10.7150/thno.51390 |
Ejemplares similares
-
Brain-Derived Neurotrophic Factor Precursor in the Hippocampus Regulates Both Depressive and Anxiety-Like Behaviors in Rats
por: Zhong, Feng, et al.
Publicado: (2019) -
Peripheral Brain Derived Neurotrophic Factor Precursor Regulates Pain as an Inflammatory Mediator
por: Luo, Cong, et al.
Publicado: (2016) -
Brain‐Derived Neurotrophic Factor Precursor Contributes to a Proinflammatory Program in Monocytes/Macrophages After Acute Myocardial Infarction
por: Li, Jia‐Nan, et al.
Publicado: (2023) -
Up-regulation of proBDNF/p75(NTR) signaling in antibody-secreting cells drives systemic lupus erythematosus
por: Shen, Wei-Yun, et al.
Publicado: (2022) -
Neuroimmune crosstalk through brain-derived neurotrophic factor and its precursor pro-BDNF: New insights into mood disorders
por: Zhao, Xiao-Pei, et al.
Publicado: (2022)