Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling

Glioblastoma (GBM) is the most lethal primary brain tumor in adults with a median survival of around 15 months. A potential treatment strategy involves targeting glioma stem-like cells (GSCs) that are able to initiate, maintain, and repopulate the tumor mass. Here, we identify ACT001, a parthenolide...

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Detalles Bibliográficos
Autores principales: Hou, Yanli, Sun, Bowen, Liu, Wenxue, Yu, Bo, Shi, Qiqi, Luo, Fei, Bai, Yongrui, Feng, Haizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738851/
https://www.ncbi.nlm.nih.gov/pubmed/33391492
http://dx.doi.org/10.7150/thno.49250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738851/
https://www.ncbi.nlm.nih.gov/pubmed/33391492
http://dx.doi.org/10.7150/thno.49250

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