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PLAGL2 promotes the proliferation and migration of gastric cancer cells via USP37-mediated deubiquitination of Snail1

Rationale: PLAGL2 (pleomorphic adenoma gene like-2), a zinc finger PLAG transcription factor, is aberrantly expressed in several malignant tumors. However, the biological roles of PLAGL2 and its underlying mechanism in gastric cancer (GC) remain unclear. Methods: A series of experiments in vitro and...

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Detalles Bibliográficos
Autores principales: Wu, Liang, Zhao, Ning, Zhou, Zili, Chen, Jinhuang, Han, Shengbo, Zhang, Xudan, Bao, Haijun, Yuan, Wenzheng, Shu, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738862/
https://www.ncbi.nlm.nih.gov/pubmed/33391500
http://dx.doi.org/10.7150/thno.47800