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A novel STAT3 inhibitor W2014-S regresses human non-small cell lung cancer xenografts and sensitizes EGFR-TKI acquired resistance

Constitutive activation of signal transducer and activator of transcription 3 (STAT3) is a common feature in human non-small cell lung cancer (NSCLC). STAT3 plays an important role in cancer progression as a driver oncogene and acquired resistance of targeted therapies as an alternatively activated...

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Detalles Bibliográficos
Autores principales: Zheng, Qiyao, Dong, Hui, Mo, Jianshan, Zhang, Yi, Huang, Jie, Ouyang, Shumin, Shi, Shuo, Zhu, Kai, Qu, Xinming, Hu, Wenhao, Liu, Peiqing, Wang, Yuanxiang, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738869/
https://www.ncbi.nlm.nih.gov/pubmed/33391507
http://dx.doi.org/10.7150/thno.49600