Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis

Rationale: Although human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) transplantation has been proved to be an effective therapeutic approach to treat systemic lupus erythematosus (SLE), the detailed underlying mechanisms are not fully understood. Transferring miRNAs is one mean by whic...

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Detalles Bibliográficos
Autores principales: Cheng, Tao, Ding, Shuai, Liu, Shanshan, Li, Yan, Sun, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738872/
https://www.ncbi.nlm.nih.gov/pubmed/33391511
http://dx.doi.org/10.7150/thno.48080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738872/
https://www.ncbi.nlm.nih.gov/pubmed/33391511
http://dx.doi.org/10.7150/thno.48080

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