H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts

Background: Collagen type VI alpha 1 (COL6A1) has been found to be dysregulated in several human malignancies. However, the role of COL6A1 in osteosarcoma (OS) progression remains largely unclear. Here, we aimed to explore the clinical significance and biological involvement of COL6A1 in the OS cell...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Liu, Zhaoyong, Yang, Xia, Lu, Weiqing, Chen, Yelong, Lin, Youbin, Wang, Jin, Lin, Suxia, Yun, Jing-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738898/
https://www.ncbi.nlm.nih.gov/pubmed/33391546
http://dx.doi.org/10.7150/thno.51245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738898/
https://www.ncbi.nlm.nih.gov/pubmed/33391546
http://dx.doi.org/10.7150/thno.51245

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