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M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice

Rationale: Glial scars present a major obstacle for neuronal regeneration after stroke. Thus, approaches to promote their degradation and inhibit their formation are beneficial for stroke recovery. The interaction of microglia and astrocytes is known to be involved in glial scar formation after stro...

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Detalles Bibliográficos
Autores principales: Li, Zongwei, Song, Yaying, He, Tingting, Wen, Ruoxue, Li, Yongfang, Chen, Tingting, Huang, Shuxian, Wang, Yongting, Tang, Yaohui, Shen, FanXia, Tian, Heng-Li, Yang, Guo-Yuan, Zhang, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738903/
https://www.ncbi.nlm.nih.gov/pubmed/33391532
http://dx.doi.org/10.7150/thno.48761