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Inhibition of USP1 induces apoptosis via ID1/AKT pathway in B-cell acute lymphoblastic leukemia cells

Deubiquitylating enzyme ubiquitin-specific protease 1 (USP1) has been reported to be aberrantly overexpressed in cancers, and it plays a critical role in regulating various cellular processes, such as cell proliferation, apoptosis, and cell differentiation. However, the role of USP1 in B-cell acute...

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Detalles Bibliográficos
Autores principales: Kuang, Xingyi, Xiong, Jie, Lu, Tingting, Wang, Weili, Zhang, Zhaoyuan, Wang, Jishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738972/
https://www.ncbi.nlm.nih.gov/pubmed/33390793
http://dx.doi.org/10.7150/ijms.47597