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Regulation and biological functions of the CX3CL1-CX3CR1 axis and its relevance in solid cancer: A mini-review

CX3CL1 is a transmembrane protein from which a soluble form can be generated by proteolytic shedding. Membranal and soluble forms of CX3CL1 exhibit different functions, although both bind to the CX3CR1 chemokine receptor. The CX3CL1-CX3CR1 axis mediates the adhesion of leukocytes and is also involve...

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Detalles Bibliográficos
Autores principales: Rivas-Fuentes, Selma, Salgado-Aguayo, Alfonso, Arratia-Quijada, Jenny, Gorocica-Rosete, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738983/
https://www.ncbi.nlm.nih.gov/pubmed/33391453
http://dx.doi.org/10.7150/jca.47022