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Sex differences in the effect of the FKBP5 inhibitor SAFit2 on anxiety and stress-induced reinstatement following cocaine self-administration

Cocaine use and withdrawal prompt stress system responses. Stress and the negative affective state produced by cocaine withdrawal are major triggers for relapse. FKBP5 is a co-chaperone of the glucocorticoid receptor and regulates HPA axis negative feedback. The role of FKBP5 in cocaine-related beha...

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Detalles Bibliográficos
Autores principales: Connelly, Krista L., Wolsh, Cassandra C., Barr, Jeffrey L., Bauder, Michael, Hausch, Felix, Unterwald, Ellen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739032/
https://www.ncbi.nlm.nih.gov/pubmed/33344688
http://dx.doi.org/10.1016/j.ynstr.2020.100232