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Disinhibition of somatostatin interneurons confers resilience to stress in male but not female mice

Chronic stress represents a vulnerability factor for anxiety and depressive disorders and has been widely used to model aspects of these disorders in rodents. Disinhibition of somatostatin (SST)-positive GABAergic interneurons in mice by deletion of γ2 GABA(A) receptors selectively from these cells...

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Detalles Bibliográficos
Autores principales: Jefferson, Sarah J., Feng, Mengyang, Chon, URee, Guo, Yao, Kim, Yongsoo, Luscher, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739040/
https://www.ncbi.nlm.nih.gov/pubmed/33344694
http://dx.doi.org/10.1016/j.ynstr.2020.100238