Increased methylation of NR3C1 and SLC6A4 is associated with blunted cortisol reactivity to stress in major depression

BACKGROUND: Epigenetic changes are considered the main mechanisms behind the interplay of environment and genetic susceptibility in major depressive disorder (MDD). However, studies focusing on epigenetic dysregulation of the HPA axis stress response in MDD are lacking. Our objective was to simultan...

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Detalles Bibliográficos
Autores principales: Bakusic, Jelena, Vrieze, Elske, Ghosh, Manosij, Bekaert, Bram, Claes, Stephan, Godderis, Lode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739183/
https://www.ncbi.nlm.nih.gov/pubmed/33344725
http://dx.doi.org/10.1016/j.ynstr.2020.100272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739183/
https://www.ncbi.nlm.nih.gov/pubmed/33344725
http://dx.doi.org/10.1016/j.ynstr.2020.100272

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