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Increased methylation of NR3C1 and SLC6A4 is associated with blunted cortisol reactivity to stress in major depression
BACKGROUND: Epigenetic changes are considered the main mechanisms behind the interplay of environment and genetic susceptibility in major depressive disorder (MDD). However, studies focusing on epigenetic dysregulation of the HPA axis stress response in MDD are lacking. Our objective was to simultan...
Autores principales: | Bakusic, Jelena, Vrieze, Elske, Ghosh, Manosij, Bekaert, Bram, Claes, Stephan, Godderis, Lode |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739183/ https://www.ncbi.nlm.nih.gov/pubmed/33344725 http://dx.doi.org/10.1016/j.ynstr.2020.100272 |
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