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Blockade of nociceptin/orphanin FQ signaling facilitates an active copying strategy due to acute and repeated stressful stimuli in mice

The role of stress in the etiology of depression has been largely reported. In this line, exogenous glucocorticoids are employed to mimic the influence of stress on the development of depression. The N/OFQ-NOP receptor system has been implicated in the modulation of stress and emotional behaviors. I...

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Detalles Bibliográficos
Autores principales: Holanda, Victor A.D., Oliveira, Matheus C., Da Silva Junior, Edilson D., Calo', Girolamo, Ruzza, Chiara, Gavioli, Elaine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739191/
https://www.ncbi.nlm.nih.gov/pubmed/33344710
http://dx.doi.org/10.1016/j.ynstr.2020.100255