Cargando…

Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis

Aging is associated with an increase in fat mass which increases the risk for disease, morbidity and premature mortality. Creatine supplementation in combination with resistance training has been shown to increase lean tissue mass in adults ≥50 years of age; however, the synergetic effects of creati...

Descripción completa

Detalles Bibliográficos
Autores principales: Forbes, Scott C., Candow, Darren G., Krentz, Joel R., Roberts, Michael D., Young, Kaelin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739317/
https://www.ncbi.nlm.nih.gov/pubmed/33467377
http://dx.doi.org/10.3390/jfmk4030062
_version_ 1783623309074628608
author Forbes, Scott C.
Candow, Darren G.
Krentz, Joel R.
Roberts, Michael D.
Young, Kaelin C.
author_facet Forbes, Scott C.
Candow, Darren G.
Krentz, Joel R.
Roberts, Michael D.
Young, Kaelin C.
author_sort Forbes, Scott C.
collection PubMed
description Aging is associated with an increase in fat mass which increases the risk for disease, morbidity and premature mortality. Creatine supplementation in combination with resistance training has been shown to increase lean tissue mass in adults ≥50 years of age; however, the synergetic effects of creatine and resistance training on fat mass in this population are unclear. Creatine metabolism plays an important role in adipose tissue bioenergetics and energy expenditure. Thus, the combination of creatine supplementation and resistance training may decrease fat mass more than resistance training alone. The purpose of this review is two-fold: (1) to perform meta-analyses on studies involving creatine supplementation during resistance training on fat mass in adults ≥50 years of age, and (2) to discuss possible mechanistic actions of creatine on reducing fat mass. Nineteen studies were included in our meta-analysis with 609 participants. Results from the meta-analyses showed that adults ≥50 years of age who supplemented with creatine during resistance training experienced a greater reduction in body fat percentage (0.55%, p = 0.04) compared to those on placebo during resistance training. Despite no statistical difference (p = 0.13), adults supplementing with creatine lost ~0.5 kg more fat mass compared to those on placebo. Interestingly, there are studies which have linked mechanism(s) explaining how creatine may influence fat mass, and these data are also discussed.
format Online
Article
Text
id pubmed-7739317
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-77393172021-01-13 Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis Forbes, Scott C. Candow, Darren G. Krentz, Joel R. Roberts, Michael D. Young, Kaelin C. J Funct Morphol Kinesiol Review Aging is associated with an increase in fat mass which increases the risk for disease, morbidity and premature mortality. Creatine supplementation in combination with resistance training has been shown to increase lean tissue mass in adults ≥50 years of age; however, the synergetic effects of creatine and resistance training on fat mass in this population are unclear. Creatine metabolism plays an important role in adipose tissue bioenergetics and energy expenditure. Thus, the combination of creatine supplementation and resistance training may decrease fat mass more than resistance training alone. The purpose of this review is two-fold: (1) to perform meta-analyses on studies involving creatine supplementation during resistance training on fat mass in adults ≥50 years of age, and (2) to discuss possible mechanistic actions of creatine on reducing fat mass. Nineteen studies were included in our meta-analysis with 609 participants. Results from the meta-analyses showed that adults ≥50 years of age who supplemented with creatine during resistance training experienced a greater reduction in body fat percentage (0.55%, p = 0.04) compared to those on placebo during resistance training. Despite no statistical difference (p = 0.13), adults supplementing with creatine lost ~0.5 kg more fat mass compared to those on placebo. Interestingly, there are studies which have linked mechanism(s) explaining how creatine may influence fat mass, and these data are also discussed. MDPI 2019-08-23 /pmc/articles/PMC7739317/ /pubmed/33467377 http://dx.doi.org/10.3390/jfmk4030062 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Forbes, Scott C.
Candow, Darren G.
Krentz, Joel R.
Roberts, Michael D.
Young, Kaelin C.
Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis
title Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis
title_full Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis
title_fullStr Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis
title_full_unstemmed Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis
title_short Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis
title_sort changes in fat mass following creatine supplementation and resistance training in adults ≥50 years of age: a meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739317/
https://www.ncbi.nlm.nih.gov/pubmed/33467377
http://dx.doi.org/10.3390/jfmk4030062
work_keys_str_mv AT forbesscottc changesinfatmassfollowingcreatinesupplementationandresistancetraininginadults50yearsofageametaanalysis
AT candowdarreng changesinfatmassfollowingcreatinesupplementationandresistancetraininginadults50yearsofageametaanalysis
AT krentzjoelr changesinfatmassfollowingcreatinesupplementationandresistancetraininginadults50yearsofageametaanalysis
AT robertsmichaeld changesinfatmassfollowingcreatinesupplementationandresistancetraininginadults50yearsofageametaanalysis
AT youngkaelinc changesinfatmassfollowingcreatinesupplementationandresistancetraininginadults50yearsofageametaanalysis