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Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis

Corticogenesis is one of the most critical and complicated processes during embryonic brain development. Any slight impairment in corticogenesis could cause neurodevelopmental disorders such as Fragile X syndrome (FXS), of which symptoms contain intellectual disability (ID) and autism spectrum disor...

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Detalles Bibliográficos
Autores principales: Casingal, Cristine R., Kikkawa, Takako, Inada, Hitoshi, Sasaki, Yukio, Osumi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739466/
https://www.ncbi.nlm.nih.gov/pubmed/33323119
http://dx.doi.org/10.1186/s13041-020-00706-1