Increased expression of IFN-γ in preeclampsia impairs human trophoblast invasion via a SOCS1/JAK/STAT1 feedback loop

The weakening of extravillous trophoblast (EVT) invasion results in shallow placenta implantation. In HTR8/SVneo cells, IFN-γ can activate STAT1 and reduce cell invasion, and suppressor of cytokine signaling (SOCS) is an important negative regulatory protein in the Janus kinase (JAK)/STAT activator...

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Detalles Bibliográficos
Autores principales: Liu, Huiqiang, Wang, Wenhao, Liu, Chongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739872/
https://www.ncbi.nlm.nih.gov/pubmed/33335575
http://dx.doi.org/10.3892/etm.2020.9544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739872/
https://www.ncbi.nlm.nih.gov/pubmed/33335575
http://dx.doi.org/10.3892/etm.2020.9544

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