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Therapeutic Potential of TNF-α Inhibition for Alzheimer’s Disease Prevention

BACKGROUND: Alzheimer’s disease (AD) is increasingly prevalent and over 99% of drugs developed for AD have failed in clinical trials. A growing body of literature suggests that potent inhibitors of tumor necrosis factor-α (TNF-α) have potential to improve cognitive performance. OBJECTIVE: In this re...

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Detalles Bibliográficos
Autores principales: Torres-Acosta, Noel, O’Keefe, James H., O’Keefe, Evan L., Isaacson, Richard, Small, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739965/
https://www.ncbi.nlm.nih.gov/pubmed/33016914
http://dx.doi.org/10.3233/JAD-200711