Dysregulation of Insulin-Linked Metabolic Pathways in Alzheimer’s Disease: Co-Factor Role of Apolipoprotein E ɛ4

BACKGROUND: Brain insulin resistance and deficiency are well-recognized abnormalities in Alzheimer’s disease (AD) and likely mediators of impaired energy metabolism. Since apolipoprotein E (APOE) is a major risk factor for late-onset AD, it was of interest to examine its potential contribution to al...

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Detalles Bibliográficos
Autores principales: Robbins, James, Busquets, Oriol, Tong, Ming, de la Monte, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739986/
https://www.ncbi.nlm.nih.gov/pubmed/33344887
http://dx.doi.org/10.3233/ADR-200238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739986/
https://www.ncbi.nlm.nih.gov/pubmed/33344887
http://dx.doi.org/10.3233/ADR-200238

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