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Macrophage fusion caused by particle instillation

BACKGROUND: Multinucleated giant cells (MGC) are formed by fusion of macrophages in pathological conditions. These are often studied in the context of the foreign body response to biomaterial implants, but MGC formation is rarely assessed in response to inorganic particles in the lungs. Therefore, a...

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Detalles Bibliográficos
Autores principales: Trout, Kevin L., Holian, Andrij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740110/
https://www.ncbi.nlm.nih.gov/pubmed/33336194
http://dx.doi.org/10.1016/j.crtox.2020.04.003