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Epigenetic Signatures of Cell States in Aging

Epigenetic clocks based on DNA methylation (DNAm) show striking age correlations and predict various outcomes. Patterns of DNAm also reflect critical mechanisms in differentiation and proliferation. As such, an outstanding question is whether part of the signal epigenetic clocks are capturing repres...

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Detalles Bibliográficos
Autores principales: Leung, Diana, Levine, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740117/
http://dx.doi.org/10.1093/geroni/igaa057.434