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Effect of PPARγ Inhibition on Bone in Aged Animals

Aging is accompanied by bone loss and marrowfat accumulation. PPARg is a key factor regulating adipocyte differentiation. Marrowfat secretes large quantities of factors including adipokines, cytokines and chemokines that contribute to bone loss. We hypothesized that inhibition of PPARg would reduce...

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Detalles Bibliográficos
Autores principales: Shi, Xingming, Ding, Kehong, Su, Yun, Isales, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740238/
http://dx.doi.org/10.1093/geroni/igaa057.408