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Effect of PPARγ Inhibition on Bone in Aged Animals
Aging is accompanied by bone loss and marrowfat accumulation. PPARg is a key factor regulating adipocyte differentiation. Marrowfat secretes large quantities of factors including adipokines, cytokines and chemokines that contribute to bone loss. We hypothesized that inhibition of PPARg would reduce...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740238/ http://dx.doi.org/10.1093/geroni/igaa057.408 |