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A 3-Week Tryptophan-Deficient Diet Resulted in Decreased Body Weight and Increased Trabecular Bone Mass in Mice

Tryptophan is an essential amino acid with a variety of bioactive metabolites including serotonin, melatonin and nicotinamide. Dietary Trp restriction results in increased lifespan but with detrimental side effects. The initial catabolite in the Trp breakdown pathway, kynurenine, increases with agin...

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Detalles Bibliográficos
Autores principales: Isales, Carlos, Ding, Kehong, McGee-Lawrence, Meghan, Bollag, Wendy, Hill, William, Fulzele, Sadanand, Awad, Mohamed, Hamrick, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740284/
http://dx.doi.org/10.1093/geroni/igaa057.403