Cargando…

A 3-Week Tryptophan-Deficient Diet Resulted in Decreased Body Weight and Increased Trabecular Bone Mass in Mice

Tryptophan is an essential amino acid with a variety of bioactive metabolites including serotonin, melatonin and nicotinamide. Dietary Trp restriction results in increased lifespan but with detrimental side effects. The initial catabolite in the Trp breakdown pathway, kynurenine, increases with agin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Isales, Carlos, Ding, Kehong, McGee-Lawrence, Meghan, Bollag, Wendy, Hill, William, Fulzele, Sadanand, Awad, Mohamed, Hamrick, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740284/ http://dx.doi.org/10.1093/geroni/igaa057.403

Ejemplares similares

Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview
por: Vyavahare, Sagar, et al.
Publicado: (2021)

3-Hydroxyanthranilic acid Administration Did Not Prevent Age Related Bone Loss
por: Isales, Carlos, et al.
Publicado: (2021)

3-Hydroxyanthranilic acid Administration Did Not Prevent Age Related Bone Loss
por: Isales, Carlos, et al.
Publicado: (2021)

A Tryptophan-Deficient Diet Induces Gut Microbiota Dysbiosis and Increases Systemic Inflammation in Aged Mice
por: Yusufu, Ibrahim, et al.
Publicado: (2021)

Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation
por: Kaiser, Helen, et al.
Publicado: (2019)

PICOLINIC ACID, A TRYPTOPHAN METABOLITE, DOESN’T AFFECT BONE MINERAL DENSITY BUT UPREGULATES LIPID STORAGE GENES
por: Isales, Carlos, et al.
Publicado: (2019)

Depletion of the miR-34a “sponge” MALAT1 in aging skeletal muscle: Implications for age-related muscle loss
por: Ruan, Ling, et al.
Publicado: (2021)

The Kynurenine Pathway Metabolites QA and KYNA induce senescence in Bone Marrow Stem Cells through the AhR Pathway
por: Kondrikov, Dmitry, et al.
Publicado: (2021)

KYNURENINE, AN ENDOGENOUS AHR AGONIST, UPREGULATES CXCL12- AND HDAC3-TARGETING MIRNAS INHIBITING OSTEOGENESIS
por: Elmansi, Ahmed M, et al.
Publicado: (2019)

AGE-ASSOCIATED INCREASE IN KYNURENINE INHIBITS AUTOPHAGY AND PROMOTES SENESCENCE IN BONE MARROW STEM CELLS
por: Kondrikov, Dmitry, et al.
Publicado: (2019)

The Role of Tryptophan Metabolites in Musculoskeletal Stem Cell Aging
por: Anaya, Jordan Marcano, et al.
Publicado: (2020)

Long Non-coding RNA MALAT1 Is Depleted With Age in Skeletal Muscle in vivo and MALAT1 Silencing Increases Expression of TGF-β1 in vitro
por: Ruan, Ling, et al.
Publicado: (2022)

Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics
por: Burke, John, et al.
Publicado: (2016)

Therapeutic potential of mesenchymal stem cell based therapy for osteoarthritis
por: Burke, John, et al.
Publicado: (2016)

Kynurenine Promotes RANKL-Induced Osteoclastogenesis In Vitro by Activating the Aryl Hydrocarbon Receptor Pathway
por: Eisa, Nada H., et al.
Publicado: (2020)

Stromal cell-derived factor-1 as a potential therapeutic target for osteoarthritis and rheumatoid arthritis
por: Bragg, Robert, et al.
Publicado: (2019)

AGE-ASSOCIATED INCREASE IN KYNURENINE SUPPRESSES AUTOPHAGY AND PROMOTES APOPTOSIS IN MESENCHYMAL STEM CELLS
por: Kondrikov, Dmitry, et al.
Publicado: (2019)

Synergistic Effects of Multiple Factors Involved in COVID-19-dependent Muscle Loss
por: Cantu, Nicholas, et al.
Publicado: (2022)

Low level of Vitamin C and dysregulation of Vitamin C transporter might be involved in the severity of COVID-19 Infection
por: Patterson, Taylor, et al.
Publicado: (2021)

Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells
por: Fulzele, Sadanand, et al.
Publicado: (2019)

Recent advances in hyaluronic acid based therapy for osteoarthritis
por: Bowman, Steven, et al.
Publicado: (2018)

The Senolytic Drug Navitoclax (ABT-263) Causes Trabecular Bone Loss and Impaired Osteoprogenitor Function in Aged Mice
por: Sharma, Anuj K., et al.
Publicado: (2020)

Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells
por: Elmansi, Ahmed M., et al.
Publicado: (2020)

Whole-Body Vibration Mimics the Metabolic Effects of Exercise in Male Leptin Receptor–Deficient Mice
por: McGee-Lawrence, Meghan E., et al.
Publicado: (2017)

Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment
por: Awad, Mohamed E., et al.
Publicado: (2019)

Modulation of miRNAs by Vitamin C in Human Bone Marrow Stromal Cells
por: Kolhe, Ravindra, et al.
Publicado: (2018)

Inhibiting MicroRNA-141-3p Improves Musculoskeletal Health in Aged Mice
por: Vyavahare, Sagar, et al.
Publicado: (2023)

Absence of Functional Leptin Receptor Isoforms in the POUND (Lepr(db/lb)) Mouse Is Associated with Muscle Atrophy and Altered Myoblast Proliferation and Differentiation
por: Arounleut, Phonepasong, et al.
Publicado: (2013)

Correction: Absence of Functional Leptin Receptor Isoforms in the POUND (Lepr(db/lb)) Mouse Is Associated with Muscle Atrophy and Altered Myoblast Proliferation and Differentiation
por: Arounleut, Phonepasong, et al.
Publicado: (2013)

Function of microRNAs in the Osteogenic Differentiation and Therapeutic Application of Adipose-Derived Stem Cells (ASCs)
por: Hodges, Walter M., et al.
Publicado: (2017)

Extracellular Vesicles as Communicators of Senescence in Musculoskeletal Aging
por: Alfonzo, Monica Correa, et al.
Publicado: (2022)

GRowing an Epidermal Tumor
por: Bollag, Wendy B., et al.
Publicado: (2013)

Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues
por: Blackburn, Alan R, et al.
Publicado: (2014)

Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice
por: Pandya, Chirayu D., et al.
Publicado: (2019)

Decreased pericellular matrix production and selection for enhanced cell membrane repair may impair osteocyte responses to mechanical loading in the aging skeleton
por: Hagan, Mackenzie L., et al.
Publicado: (2019)

Fatty Infiltration of Skeletal Muscle: Mechanisms and Comparisons with Bone Marrow Adiposity
por: Hamrick, Mark W., et al.
Publicado: (2016)

Extracellular vesicles in the pathogenesis of rheumatoid arthritis and osteoarthritis
por: Withrow, Joseph, et al.
Publicado: (2016)

Vitamin C supplementation for the treatment of osteoarthritis: perspectives on the past, present, and future
por: Dunlap, Burton, et al.
Publicado: (2021)

Sex-Specific Differences in Extracellular Vesicle Protein Cargo in Synovial Fluid of Patients with Osteoarthritis
por: Kolhe, Ravindra, et al.
Publicado: (2020)

COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile
por: Fulzele, Sadanand, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jad7vl9ut03t9urgef7rniame5