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The Quantile Frailty Index: A Cutpoint-Free Approach to Biomarker-Based Health Assessment

We develop a frailty index (FI) from continuous valued biomarker measurements that does not use thresholds to binarize deficits. In this work we construct a quantile frailty index (FI-Q) directly from risk quantiles, without binarizing the deficits. FI-Q is the average risk quantile for an individua...

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Detalles Bibliográficos
Autores principales: Stubbings, Garrett, Farrell, Spencer, Mitnitski, Arnold, Rockwood, Kenneth, Rutenberg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740510/
http://dx.doi.org/10.1093/geroni/igaa057.582