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Sex-specific BDNF and APOE ε4 genotype interactions on white matter hyperintensity volume

The apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset Alzheimer’s disease (AD). One variant of the brain-derived neurotrophic factor (BDNF) gene also confers higher risk of AD. APOE and BDNF genotypes may have interactive effects on AD pathology. The aim of this study...

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Detalles Bibliográficos
Autor principal: Pitts, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7740536/
http://dx.doi.org/10.1093/geroni/igaa057.3252