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Cell-Based and Pharmacologic Hormone Therapy Maintain Diastolic Function After Ovariectomy in Hypertensive Rats

The role for hormone therapy in the maintenance of diastolic function upon ovarian senescence has not been clinically tested due to concerns for off-target health risks. We developed a cell-based hormone therapy (cHT) approach that recapitulates native cell–cell interactions between ovarian granulos...

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Detalles Bibliográficos
Autores principales: Groban, Leanne, Sun, Xuming, Sivanandane, Sittadjody, Hodge, Hunter, Wang, Hao, Lin, Marina, Opara, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741154/
http://dx.doi.org/10.1093/geroni/igaa057.429