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Interactions Between Genes From Aging Pathways Significantly Influence Risk of Alzheimer’s Disease

Age is major risk factor for AD; however, relationships between aging and AD are not well understood. Decline in physiological resilience is universal feature of human aging that may also play role in AD. Aging-related pathways (such as IGF-I/P53/mTOR-mediated) that are involved in tissue resilience...

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Detalles Bibliográficos
Autores principales: Ukraintseva, Svetlana, Arbeev, Konstantin, Duan, Hongzhe, Akushevich, Igor, Feitosa, Mary, Christensen, Kaare, Stallard, Eric, Yashin, Anatoliy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741718/
http://dx.doi.org/10.1093/geroni/igaa057.467