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NMN Rescues Endothelial Function and Neurovascular Coupling, Improving Cognitive Function in Aged Mice

Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function. In aging increased oxidative stress and cerebromicrovascular endothelial dysfunction impair NVC, contributing to cognitive decline. There...

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Detalles Bibliográficos
Autores principales: Tarantini, Stefano, Yabluchanskiy, Andriy, Ballabh, Praveen, Farkas, Eszter, Baur, Joseph, Sinclair, David, Csiszar, Anna, Ungvari, Zoltan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741797/
http://dx.doi.org/10.1093/geroni/igaa057.399