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NMN Rescues Endothelial Function and Neurovascular Coupling, Improving Cognitive Function in Aged Mice
Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function. In aging increased oxidative stress and cerebromicrovascular endothelial dysfunction impair NVC, contributing to cognitive decline. There...
Autores principales: | Tarantini, Stefano, Yabluchanskiy, Andriy, Ballabh, Praveen, Farkas, Eszter, Baur, Joseph, Sinclair, David, Csiszar, Anna, Ungvari, Zoltan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741797/ http://dx.doi.org/10.1093/geroni/igaa057.399 |
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