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Low Dose Brain Radiation Reduces Elevated Plasma Branch Chain Amino Acid Levels in APP/PS1 Mice

Branch Chain Amino Acids (BCAA) have recently been implicated in Alzheimer’s Disease (AD). We previously showed that low dose brain radiation (RT) [5 fractions of 2 Gy] reduces amyloid-beta plaque burden and results in improved cognition in the APP/PS1 model of AD. In this study we investigated whet...

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Detalles Bibliográficos
Autores principales: Maddens, Michael, Wilson, George, Graham, Stewart, Yilmaz, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742009/
http://dx.doi.org/10.1093/geroni/igaa057.397