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Spike Protein of SARS-CoV-2 Activates Macrophages and Contributes to Induction of Acute Lung Inflammations in Mice

BACKGROUND: Coronavirus disease 2019 (COVID-19) patients exhibit multiple organ malfunctions with a primary manifestation of acute and diffuse lung injuries. The Spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial to mediate viral entry into host cells; however,...

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Detalles Bibliográficos
Autores principales: Cao, Xiaoling, Tian, Yan, Nguyen, Vi, Zhang, Yuping, Gao, Chao, Yin, Rong, Carver, Wayne, Fan, Daping, Albrecht, Helmut, Cui, Taixing, Tan, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743069/
https://www.ncbi.nlm.nih.gov/pubmed/33330865
http://dx.doi.org/10.1101/2020.12.07.414706