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Spike Protein of SARS-CoV-2 Activates Macrophages and Contributes to Induction of Acute Lung Inflammations in Mice
BACKGROUND: Coronavirus disease 2019 (COVID-19) patients exhibit multiple organ malfunctions with a primary manifestation of acute and diffuse lung injuries. The Spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial to mediate viral entry into host cells; however,...
Autores principales: | Cao, Xiaoling, Tian, Yan, Nguyen, Vi, Zhang, Yuping, Gao, Chao, Yin, Rong, Carver, Wayne, Fan, Daping, Albrecht, Helmut, Cui, Taixing, Tan, Wenbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743069/ https://www.ncbi.nlm.nih.gov/pubmed/33330865 http://dx.doi.org/10.1101/2020.12.07.414706 |
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