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Senescence and Its Role in Fibrosis

The presence of senescent cells (epithelial and mesenchymal) in fibrotic organs has been well established. Removal of senescent cells in animal models of fibrosis indicate an overall beneficial effect. The general consensus is that the senescent cells contribute to the fibrotic phenotype by the secr...

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Detalles Bibliográficos
Autor principal: Saux, Claude Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743468/
http://dx.doi.org/10.1093/geroni/igaa057.2699