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Pervasive Selection against MicroRNA Target Sites in Human Populations

MicroRNA target sites are often conserved during evolution and purifying selection to maintain such sites is expected. On the other hand, comparative analyses identified a paucity of microRNA target sites in coexpressed transcripts, and novel target sites can potentially be deleterious. We proposed...

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Detalles Bibliográficos
Autores principales: Hatlen, Andrea, Marco, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743725/
https://www.ncbi.nlm.nih.gov/pubmed/32585012
http://dx.doi.org/10.1093/molbev/msaa155