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Pervasive Selection against MicroRNA Target Sites in Human Populations
MicroRNA target sites are often conserved during evolution and purifying selection to maintain such sites is expected. On the other hand, comparative analyses identified a paucity of microRNA target sites in coexpressed transcripts, and novel target sites can potentially be deleterious. We proposed...
Autores principales: | Hatlen, Andrea, Marco, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743725/ https://www.ncbi.nlm.nih.gov/pubmed/32585012 http://dx.doi.org/10.1093/molbev/msaa155 |
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