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Sex Differences in Response to Metformin in a Longitudinal Study in Mice

Sexual dimorphisms have been recognized in most aspects of human health and disease, and there is now clear evidence for more pronounced differences in response to pharmacological interventions of aging. Here, male and female C57BL/6J mice at six months of age were administered 0.5% metformin in the...

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Detalles Bibliográficos
Autores principales: Teixeira, Camila Vieira Ligo, Alfaras, Irene, Camadola, Simonetta, Price, Nathan, Bernier, Michel, de Cabo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743759/
http://dx.doi.org/10.1093/geroni/igaa057.1673