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Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study

BACKGROUND: The optimal treatment for patients with severe coronavirus-19 disease (COVID-19) and hyper-inflammation remains debated. MATERIAL AND METHODS: A cohort study was designed to evaluate whether a therapeutic algorithm using steroids with or without interleukin-1 antagonist (anakinra) could...

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Detalles Bibliográficos
Autores principales: Borie, Raphael, Savale, Laurent, Dossier, Antoine, Ghosn, Jade, Taillé, Camille, Visseaux, Benoit, Jebreen, Kamel, Diallo, Abourahmane, Tesmoingt, Chloe, Morer, Lise, Goletto, Tiphaine, Faucher, Nathalie, Hajouji, Linda, Neukirch, Catherine, Phillips, Mathilde, Stelianides, Sandrine, Bouadma, Lila, Brosseau, Solenn, Ottaviani, Sébastien, Pluvy, Johan, Le Pluart, Diane, Debray, Marie-Pierre, Raynaud-Simon, Agathe, Descamps, Diane, Khalil, Antoine, Timsit, Jean Francois, Lescure, Francois-Xavier, Descamps, Vincent, Papo, Thomas, Humbert, Marc, Crestani, Bruno, Dieude, Philippe, Vicaut, Eric, Zalcman, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743937/
https://www.ncbi.nlm.nih.gov/pubmed/33326457
http://dx.doi.org/10.1371/journal.pone.0243961