Activation of neuronal adenosine A(1) receptors causes hypothermia through central and peripheral mechanisms

Extracellular adenosine, a danger signal, can cause hypothermia. We generated mice lacking neuronal adenosine A(1) receptors (A(1)AR, encoded by the Adora1 gene) to examine the contribution of these receptors to hypothermia. Intracerebroventricular injection of the selective A(1)AR agonist (Cl-ENBA,...

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Detalles Bibliográficos
Autores principales: Province, Haley S., Xiao, Cuiying, Mogul, Allison S., Sahoo, Ankita, Jacobson, Kenneth A., Piñol, Ramón A., Gavrilova, Oksana, Reitman, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743955/
https://www.ncbi.nlm.nih.gov/pubmed/33326493
http://dx.doi.org/10.1371/journal.pone.0243986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743955/
https://www.ncbi.nlm.nih.gov/pubmed/33326493
http://dx.doi.org/10.1371/journal.pone.0243986

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