Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

Chronic inflammation promotes prostate cancer (PCa) initiation and progression. We previously reported that acute intereluekin-1 (IL-1) exposure represses androgen receptor (AR) accumulation and activity, providing a possible mechanism for IL-1-mediated development of androgen- and AR-independent PC...

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Detalles Bibliográficos
Autores principales: Dahl, Haley C., Kanchwala, Mohammed, Thomas-Jardin, Shayna E., Sandhu, Amrit, Kanumuri, Preethi, Nawas, Afshan F., Xing, Chao, Lin, Chenchu, Frigo, Daniel E., Delk, Nikki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743957/
https://www.ncbi.nlm.nih.gov/pubmed/33326447
http://dx.doi.org/10.1371/journal.pone.0242970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743957/
https://www.ncbi.nlm.nih.gov/pubmed/33326447
http://dx.doi.org/10.1371/journal.pone.0242970

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