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Characterization of constitutive ER-phagy of excess membrane proteins

Thirty percent of all cellular proteins are inserted into the endoplasmic reticulum (ER), which spans throughout the cytoplasm. Two well-established stress-induced pathways ensure quality control (QC) at the ER: ER-phagy and ER-associated degradation (ERAD), which shuttle cargo for degradation to th...

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Detalles Bibliográficos
Autores principales: Lipatova, Zhanna, Gyurkovska, Valeriya, Zhao, Sarah F., Segev, Nava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744050/
https://www.ncbi.nlm.nih.gov/pubmed/33275594
http://dx.doi.org/10.1371/journal.pgen.1009255