Cargando…

Halogenated tryptophan derivatives disrupt essential transamination mechanisms in bloodstream form Trypanosoma brucei

Amino acid metabolism within Trypanosoma brucei, the causative agent of human African trypanosomiasis, is critical for parasite survival and virulence. Of these metabolic processes, the transamination of aromatic amino acids is one of the most important. In this study, a series of halogenated trypto...

Descripción completa

Detalles Bibliográficos
Autores principales: Cockram, Peter E., Dickie, Emily A., Barrett, Michael P., Smith, Terry K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744056/
https://www.ncbi.nlm.nih.gov/pubmed/33275612
http://dx.doi.org/10.1371/journal.pntd.0008928