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Halogenated tryptophan derivatives disrupt essential transamination mechanisms in bloodstream form Trypanosoma brucei
Amino acid metabolism within Trypanosoma brucei, the causative agent of human African trypanosomiasis, is critical for parasite survival and virulence. Of these metabolic processes, the transamination of aromatic amino acids is one of the most important. In this study, a series of halogenated trypto...
Autores principales: | Cockram, Peter E., Dickie, Emily A., Barrett, Michael P., Smith, Terry K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744056/ https://www.ncbi.nlm.nih.gov/pubmed/33275612 http://dx.doi.org/10.1371/journal.pntd.0008928 |
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