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De novo synthesis and salvage pathway coordinately regulate polyamine homeostasis and determine T cell proliferation and function
Robust and effective T cell–mediated immune responses require proper allocation of metabolic resources through metabolic pathways to sustain the energetically costly immune response. As an essential class of polycationic metabolites ubiquitously present in all living organisms, the polyamine pool is...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744078/ https://www.ncbi.nlm.nih.gov/pubmed/33328226 http://dx.doi.org/10.1126/sciadv.abc4275 |