De novo synthesis and salvage pathway coordinately regulate polyamine homeostasis and determine T cell proliferation and function

Robust and effective T cell–mediated immune responses require proper allocation of metabolic resources through metabolic pathways to sustain the energetically costly immune response. As an essential class of polycationic metabolites ubiquitously present in all living organisms, the polyamine pool is...

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Detalles Bibliográficos
Autores principales: Wu, Ruohan, Chen, Xuyong, Kang, Siwen, Wang, Tingting, Gnanaprakasam, JN Rashida, Yao, Yufeng, Liu, Lingling, Fan, Gaofeng, Burns, Mark R., Wang, Ruoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744078/
https://www.ncbi.nlm.nih.gov/pubmed/33328226
http://dx.doi.org/10.1126/sciadv.abc4275

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