An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility

Synaptic weight changes among postsynaptic densities within a single dendrite are regulated by the balance between localized protein degradation and synthesis. However, the molecular mechanism via these opposing regulatory processes is still elusive. Here, we showed that the molecular motor KIF17 wa...

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Detalles Bibliográficos
Autores principales: Iwata, Suguru, Morikawa, Momo, Takei, Yosuke, Hirokawa, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744090/
https://www.ncbi.nlm.nih.gov/pubmed/33328231
http://dx.doi.org/10.1126/sciadv.abc8355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744090/
https://www.ncbi.nlm.nih.gov/pubmed/33328231
http://dx.doi.org/10.1126/sciadv.abc8355

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