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An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility
Synaptic weight changes among postsynaptic densities within a single dendrite are regulated by the balance between localized protein degradation and synthesis. However, the molecular mechanism via these opposing regulatory processes is still elusive. Here, we showed that the molecular motor KIF17 wa...
Autores principales: | Iwata, Suguru, Morikawa, Momo, Takei, Yosuke, Hirokawa, Nobutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744090/ https://www.ncbi.nlm.nih.gov/pubmed/33328231 http://dx.doi.org/10.1126/sciadv.abc8355 |
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